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Generated: September 22, 2019

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Patent: 5,079,160

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Summary for Patent: 5,079,160
Title: Method to isolate clusters of cell subtypes from organs
Abstract:A method to obtain purified, well-defined cell populations from intact organs uses digestion of the distended organ with suitable proteolytic enzymes and harvest of the cell subpopulation by screening the effluent from treatment of the organ with physiologically compatible medium by a filtration screen permitting the passage of the desired cells or clusters of cells, but preventing the passage of larger particles. In this manner, physical/mechanical disruption of the cell population is unnecessary, and the cells or clusters are eased out of their structural matrix and harvested directly. Application of this method to the preparation of purified Islets of Langerhans from intact pancreas is described.
Inventor(s): Lacy; Paul E. (St. Louis, MO), Scharp; David W. (St. Louis, MO), Ricordi; Camillo (20121 Milano, IT)
Application Number:07/059,125
Patent Claims:see list of patent claims

Details for Patent 5,079,160

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Advance Biofactures SANTYL collagenase VIAL 101995 001 1965-06-04   Try a Free Trial 2036-04-30 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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