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Last Updated: December 2, 2021

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Patent: 5,045,468

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Summary for Patent: 5,045,468
Title: Protein-free culture medium which promotes hybridoma growth
Abstract:A chemically-defined, stable, protein-free medium has been devised which is capable of supporting the growth of lymphoid cells, particularly hybridomas, even in anchorage-independent cultures. Doubling rates are close to those obtained with serum-supplemented media. The medium preferably comprises a nonproteinaceous organo-iron compound, especially a nitroprusside salt, an iron chelator such as EDTA, and a selenium compound, such as selenium dioxide or sodium selenite.
Inventor(s): Darfler; Frederick J. (Derwood, MD)
Assignee: Cell Enterprises, Inc. (Harrisonburg, VA)
Application Number:07/394,082
Patent Claims:see list of patent claims

Details for Patent 5,045,468

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Recordati Rare Diseases, Inc. PANHEMATIN hemin for injection For Injection 101246 1983-07-20 ⤷  Free Forever Trial 2008-09-03
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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Serving leading biopharmaceutical companies globally:

Boehringer Ingelheim
Express Scripts
Johnson and Johnson

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