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Last Updated: September 29, 2020

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Patent: 5,008,283

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Summary for Patent: 5,008,283
Title: Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase
Abstract:This invention relates to the use of tenidap, 5-chloro-2,3-dihydro-2-oxo-3-(2-thienylcarbonyl)-indole-1-carboxamide, and the pharmaceutically-acceptable base salts thereof to inhibit activation of collagenase in a mammal and to inhibit the activity of myeloperoxidase in a mammal. This invention also relates to the use of tenidap and its salts for treating collagenase mediated disorders and diseases such as bone resorption disorders, corneal ulceration, periodontal disease, inflammatory disease and wounds of the skin and burns in mammals. The methods of this invention comprise administering an effective amount of tenidap or salts thereof to a mammal.
Inventor(s): Blackburn, Jr.; Warren D. (Groton, CT), Loose; Leland D. (Groton, CT)
Assignee: Pfizer Inc. (New York, NY)
Application Number:07/495,868
Patent Claims:see list of patent claims

Details for Patent 5,008,283

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Pfizer Inc. (New York, NY) 2039-02-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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