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Last Updated: August 3, 2021

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Patent: 4,978,332

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Summary for Patent: 4,978,332
Title: Treatments employing vasoconstrictive substances in combination with cytotoxic agents for introduction into cellular lesion areas
Abstract:A pharmaceutical composition and method of treating cellular disorders involving abnormal solid cellular growths which comprises administering a pharmaceutical composition containing cytotoxic agents in combination with a vasoconstrictive drug. Enhanced effectiveness of the composition is observed, with reduced cytotoxic effects on cells distant from the site of introduction. Agents may be included to enhance therapeutic gain and reduce adverse affects to normal tissue.
Inventor(s): Luck; Edward E. (Menlo Park, CA), Brown; Dennis M. (Menlo Park, CA)
Assignee: Matrix Pharmaceutical, Inc. (Menlo Park, CA)
Application Number:07/101,599
Patent Claims:see list of patent claims

Details for Patent 4,978,332

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04 ⤷  Try it Free Matrix Pharmaceutical, Inc. (Menlo Park, CA) 2039-03-29 RX search
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10 ⤷  Try it Free Matrix Pharmaceutical, Inc. (Menlo Park, CA) 2039-03-29 RX search
Discure Medical, Llc CHYMODIACTIN chymopapain INJECTABLE;INJECTION 018663 002 1984-07-09 ⤷  Try it Free Matrix Pharmaceutical, Inc. (Menlo Park, CA) 2039-03-29 DISCN search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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