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Last Updated: August 5, 2021

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Patent: 4,918,105

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Summary for Patent: 4,918,105
Title: Novel compounds with collagenase-inhibiting activity, a process for their preparation and pharmaceutical compositions in which these compounds are present
Abstract:The present invention relates to a novel family of chemical compounds possessing a pharmacological activity, in particular a collagenase-inhibiting activity, a process for the production of these compounds and pharmaceutical compositions in which they are present. According to the invention, these compounds correspond to the general formula: ##STR1## in which: W represents an amino acid residue selected from the group comprising valine, lysine, norleucine and methionine, and Z represents an amino radical or an alkylamino radical of which the alkyl part, which contains 1 or 2 carbon atoms, is substituted by a phenyl or trifluorophenyl radical, and also include their diastereoisomers and their addition salts with pharmaceutically acceptable acids. The invention is applicable especially in the pharmaceutical industry.
Inventor(s): Cartwright; Terence (Saint Epain, FR), Bouboutou-Tello; Romaine (Arceuil, FR), Lelievre; Yves (Tours, FR), Fournier-Zaluski; Marie-Claude (Paris, FR)
Assignee: SA Laboratoire Roger Bellon (Neuilly-Sur-Seine, FR)
Application Number:07/141,072
Patent Claims:see list of patent claims

Details for Patent 4,918,105

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04 ⤷  Try it Free SA Laboratoire Roger Bellon (Neuilly-Sur-Seine, FR) 2007-04-17 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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