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Last Updated: September 30, 2020

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Patent: 4,780,408

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Summary for Patent: 4,780,408
Title: Antibody for detection and quantification of trifluralin
Abstract:An antibody specific to trifluralin can be produced by first substituting a soluble, straight chain amino acid for a propyl group of .alpha.,.alpha., .alpha.-trifluoro-2,6-dinitro-N-N-dipropyl-p-toluidine. The trifluoro group at the 4 position, the nitro group at the 2 position and the other nitro group at the 6 position are left exposed. Thereafter, the resulting substitution product is conjugated, at the site of the substituted amino acid group, with a lysine-rich protein. The resulting compound is then used as an antigen to evoke an immune response in a host animal or antibody producing cell line. The antibody produced against the antigen is then harvested and used in an assay such as a radioimmunoassay or enzyme linked immunosorbant assay (ELISA) to determine the presence and concentrations of trifluralin in agriculturally significant substances such as plant materials, soil and water or to otherwise test for trifluralin contamination of water, food and air.
Inventor(s): Dunbar; Bohn D. (Akron, CO), Niswender; Gordon D. (Fort Collins, CO), Hudson; James M. (Fort Collins, CO)
Assignee: Colorado State University Research Foundation (Fort Collins, CO)
Application Number:06/844,338
Patent Claims:see list of patent claims

Details for Patent 4,780,408

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Grifols Usa, Llc PLASBUMIN albumin (human) SOLUTION 101138 1 1994-09-26   Start Trial Colorado State University Research Foundation (Fort Collins, CO) 2040-01-28 search
Baxalta Us Inc. FLEXBUMIN albumin human INJECTION, SOLUTION 101452 1 2014-07-31   Start Trial Colorado State University Research Foundation (Fort Collins, CO) 2040-01-28 search
Csl Behring Ag ALBURX albumin (human) SOLUTION 102366 1 2009-01-06   Start Trial Colorado State University Research Foundation (Fort Collins, CO) 2040-01-28 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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