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Last Updated: September 23, 2020

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Patent: 4,762,707

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Summary for Patent: 4,762,707
Title: New conjugates associating, by covalent bond, an enzyme with an antibody, and medicinal associations using the said conjugates
Abstract:The present invention relates to new immunoenzymic conjugates resulting from a chemical coupling, by covalent bond, of an antibody or a fragment of antibody, which has retained the capacity of recognizing the selected antigen, with an enzyme capable of producing ammonium ions from natural substrates which are well tolerated in higher animal organisms. The invention also relates to a process for the preparation of these conjugates and the medicinal associations of said conjugates with an immunotoxin.
Inventor(s): Jansen; Franz (St. Mathieu De Treviers, FR), Gros; Pierre (Montpellier, FR)
Assignee: Sanofi (Societe Anonyme) (Paris, FR)
Application Number:06/736,334
Patent Claims:see list of patent claims

Details for Patent 4,762,707

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Start Trial Sanofi (Societe Anonyme) (Paris, FR) 2005-08-09 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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