DrugPatentWatch Database Preview
Patent: 4,692,433
Summary for Patent: 4,692,433
| Title: | Method and composition for regulating serum calcium levels of mammals |
| Abstract: | Method for regulating serum calcium levels in mammals by orally administering a composition which includes a polypeptide hormone such as parathyroid hormone (PTH) or calcitonin. The polypeptide hormone is protected from destruction in the digestive tract by encapsulation in liposomes. The liposome preferably includes a cationic amphiphilic agent so that the surface of the liposome has a net positive charge. Agents for enhancing the action of the liposome encapsulated hormones are also disclosed. |
| Inventor(s): | Hostetler; Karl Y. (Del Mar, CA), Deftos; Leonard J. (Del Mar, CA) |
| Assignee: | The Regents of the University of California (Berkeley, CA) |
| Application Number: | 06/761,751 |
| Patent Claims: | see list of patent claims |
Details for Patent 4,692,433
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nps Pharms Inc | NATPARA | parathyroid hormone | INJECTABLE;INJECTION | 125511 | 001 | 2015-01-23 | Start Trial | The Regents of the University of California (Berkeley, CA) | 2004-09-08 | RX | Orphan | search |
| Nps Pharms Inc | NATPARA | parathyroid hormone | INJECTABLE;INJECTION | 125511 | 002 | 2015-01-23 | Start Trial | The Regents of the University of California (Berkeley, CA) | 2004-09-08 | RX | Orphan | search |
| Nps Pharms Inc | NATPARA | parathyroid hormone | INJECTABLE;INJECTION | 125511 | 003 | 2015-01-23 | Start Trial | The Regents of the University of California (Berkeley, CA) | 2004-09-08 | RX | Orphan | search |
| Nps Pharms Inc | NATPARA | parathyroid hormone | INJECTABLE;INJECTION | 125511 | 004 | 2015-01-23 | Start Trial | The Regents of the University of California (Berkeley, CA) | 2004-09-08 | RX | Orphan | search |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
International Patent Family for US Patent 4,692,433
| Country | Patent Number | Publication Date |
|---|---|---|
| Austria | 86102 | Mar 15, 1993 |
| Australia | 6148186 | Mar 05, 1987 |
| Canada | 1277595 | Dec 11, 1990 |
| Germany | 3687899 | Apr 08, 1993 |
| Germany | 3687899 | Jun 24, 1993 |
| European Patent Office | 0233901 | Mar 03, 1993 |
| European Patent Office | 0233901 | Sep 02, 1987 |
| >Country | >Patent Number | >Publication Date |
