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Patent: 4,692,433
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Summary for Patent: 4,692,433
Title: | Method and composition for regulating serum calcium levels of mammals |
Abstract: | Method for regulating serum calcium levels in mammals by orally administering a composition which includes a polypeptide hormone such as parathyroid hormone (PTH) or calcitonin. The polypeptide hormone is protected from destruction in the digestive tract by encapsulation in liposomes. The liposome preferably includes a cationic amphiphilic agent so that the surface of the liposome has a net positive charge. Agents for enhancing the action of the liposome encapsulated hormones are also disclosed. |
Inventor(s): | Hostetler; Karl Y. (Del Mar, CA), Deftos; Leonard J. (Del Mar, CA) |
Assignee: | The Regents of the University of California (Berkeley, CA) |
Application Number: | 06/761,751 |
Patent Claims: | see list of patent claims |
Details for Patent 4,692,433
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Nps Pharms Inc | NATPARA | parathyroid hormone | INJECTABLE;INJECTION | 125511 | 004 | 2015-01-23 | Start Trial | The Regents of the University of California (Berkeley, CA) | 2004-09-08 | RX | Orphan | search |
Nps Pharms Inc | NATPARA | parathyroid hormone | INJECTABLE;INJECTION | 125511 | 003 | 2015-01-23 | Start Trial | The Regents of the University of California (Berkeley, CA) | 2004-09-08 | RX | Orphan | search |
Nps Pharms Inc | NATPARA | parathyroid hormone | INJECTABLE;INJECTION | 125511 | 002 | 2015-01-23 | Start Trial | The Regents of the University of California (Berkeley, CA) | 2004-09-08 | RX | Orphan | search |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
International Patent Family for US Patent 4,692,433
Country | Patent Number | Estimated Expiration |
---|---|---|
World Intellectual Property Organization (WIPO) | 8700750 | Start Trial |
Japan | S63500378 | Start Trial |
Israel | 79547 | Start Trial |
>Country | >Patent Number | >Estimated Expiration |