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Last Updated: January 22, 2021

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Patent: 4,692,433

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Summary for Patent: 4,692,433

Title:	Method and composition for regulating serum calcium levels of mammals
Abstract:	Method for regulating serum calcium levels in mammals by orally administering a composition which includes a polypeptide hormone such as parathyroid hormone (PTH) or calcitonin. The polypeptide hormone is protected from destruction in the digestive tract by encapsulation in liposomes. The liposome preferably includes a cationic amphiphilic agent so that the surface of the liposome has a net positive charge. Agents for enhancing the action of the liposome encapsulated hormones are also disclosed.
Inventor(s):	Hostetler; Karl Y. (Del Mar, CA), Deftos; Leonard J. (Del Mar, CA)
Assignee:	The Regents of the University of California (Berkeley, CA)
Application Number:	06/761,751
Patent Claims:	see list of patent claims

Details for Patent 4,692,433

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Number	Approval Date	Patent No.	Assignee	Estimated Patent Expiration	Status	Orphan	Source
Nps Pharms Inc	NATPARA	parathyroid hormone	INJECTABLE;INJECTION	125511	004	2015-01-23	Start Trial	The Regents of the University of California (Berkeley, CA)	2004-09-08	RX	Orphan	search
Nps Pharms Inc	NATPARA	parathyroid hormone	INJECTABLE;INJECTION	125511	003	2015-01-23	Start Trial	The Regents of the University of California (Berkeley, CA)	2004-09-08	RX	Orphan	search
Nps Pharms Inc	NATPARA	parathyroid hormone	INJECTABLE;INJECTION	125511	002	2015-01-23	Start Trial	The Regents of the University of California (Berkeley, CA)	2004-09-08	RX	Orphan	search
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Number	>Approval Date	>Patent No.	>Assignee	>Estimated Patent Expiration	>Status	>Orphan	>Source

International Patent Family for US Patent 4,692,433

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	8700750	Start Trial
Japan	S63500378	Start Trial
Israel	79547	Start Trial
>Country	>Patent Number	>Estimated Expiration

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