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Generated: September 23, 2019

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Patent: 4,692,433

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Summary for Patent: 4,692,433

Title:	Method and composition for regulating serum calcium levels of mammals
Abstract:	Method for regulating serum calcium levels in mammals by orally administering a composition which includes a polypeptide hormone such as parathyroid hormone (PTH) or calcitonin. The polypeptide hormone is protected from destruction in the digestive tract by encapsulation in liposomes. The liposome preferably includes a cationic amphiphilic agent so that the surface of the liposome has a net positive charge. Agents for enhancing the action of the liposome encapsulated hormones are also disclosed.
Inventor(s):	Hostetler; Karl Y. (Del Mar, CA), Deftos; Leonard J. (Del Mar, CA)
Assignee:	The Regents of the University of California (Berkeley, CA)
Application Number:	06/761,751
Patent Claims:	see list of patent claims

Details for Patent 4,692,433

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Number	Approval Date	Patent No.	Assignee	Estimated Patent Expiration	Status	Orphan	Source
Nps Pharms Inc	NATPARA	parathyroid hormone	INJECTABLE;INJECTION	125511	001	2015-01-23	➤ Sign Up	The Regents of the University of California (Berkeley, CA)	2004-09-08	RX	Orphan	search
Nps Pharms Inc	NATPARA	parathyroid hormone	INJECTABLE;INJECTION	125511	002	2015-01-23	➤ Sign Up	The Regents of the University of California (Berkeley, CA)	2004-09-08	RX	Orphan	search
Nps Pharms Inc	NATPARA	parathyroid hormone	INJECTABLE;INJECTION	125511	003	2015-01-23	➤ Sign Up	The Regents of the University of California (Berkeley, CA)	2004-09-08	RX	Orphan	search
Nps Pharms Inc	NATPARA	parathyroid hormone	INJECTABLE;INJECTION	125511	004	2015-01-23	➤ Sign Up	The Regents of the University of California (Berkeley, CA)	2004-09-08	RX	Orphan	search
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Number	>Approval Date	>Patent No.	>Assignee	>Estimated Patent Expiration	>Status	>Orphan	>Source

International Patent Family for US Patent 4,692,433

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Country	Patent Number	Publication Date
Austria	86102	Mar 15, 1993
Australia	6148186	Mar 05, 1987
Canada	1277595	Dec 11, 1990
Germany	3687899	Apr 08, 1993
Germany	3687899	Jun 24, 1993
European Patent Office	0233901	Mar 03, 1993
>Country	>Patent Number	>Publication Date

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