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Last Updated: September 17, 2021

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Patent: 4,692,404

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Summary for Patent: 4,692,404
Title: Method of measuring biological ligand by the use of enzymes
Abstract:A method is provided which is highly sensitive and specific, and is suitable as a clinical test for the determination of physiological substances and trace components in humoral fluid. The method employs a conjugate of an enzyme capable of acting on a water-insoluble macromolecular substance and an antibody against the ligand (1) to be measured or a ligand (2) having an antigenic determinant common to one of the antigenic determinant(s) of the ligand (1). In the method of the invention, steric hindrance of the conjugate is emphasized by the enzyme reaction which is carried out at the boundary between solid phase and liquid phase.
Inventor(s): Ashihara; Yoshihiro (Tokyo, JP), Kasahara; Yasushi (Tokyo, JP)
Assignee: Fujirebio Kabushiki Kaisha (Tokyo, JP)
Application Number:06/670,764
Patent Claims:see list of patent claims

Details for Patent 4,692,404

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04 ⤷  Try it Free Fujirebio Kabushiki Kaisha (Tokyo, JP) 2003-11-18 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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