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Last Updated: September 24, 2020

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Patent: 4,687,664

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Summary for Patent: 4,687,664
Title: Method of inactivating reproducible pathogens
Abstract:There is described a method of inactivating reproducible pathogens in preparations containing plasmatic enzymes and proenzymes, activated or non-activated coagulation factors, such as Factors II, V, VII, VIII, IX, X, XIII, \"FEIBA\", prothrombin complex preparations, plasmatic inhibitors, immunoglobulins or other blood products, such as fibronectin and fibrinogen. In order to break and overcome the protective effect of proteins on pathogens by simultaneously preserving the biological activity and the molecular integrity of the proteins, the preparation is adjusted to a salt concentration of more than 0.5 molar by the addition of ammonium sulfate and is thermally treated, whereupon the ammonium sulfate is removed from the preparation.
Inventor(s): Philapitsch; Anton (Ebenfurt, AT), Wober; Gunter (Oberwaltersdorf, AT), Eibl; Johann (Vienna, AT), Schwarz; Otto (Vienna, AT)
Assignee: Immuno Aktiengesellschaft fur chemisch-medizinische Produkte (Vienna, AT)
Application Number:06/605,658
Patent Claims:see list of patent claims

Details for Patent 4,687,664

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Baxalta Incorporated FEIBA anti-inhibitor coagulant complex KIT 101447 1 1986-01-31   Start Trial Immuno Aktiengesellschaft fur chemisch-medizinische Produkte (Vienna, AT) 2004-08-18 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

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Express Scripts

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