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Last Updated: September 26, 2022

Patent: 4,645,668

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Summary for Patent: 4,645,668
Title: Method for the prevention and treatment of scars with enzymes
Abstract:The method for preventing and for treating mammalian cicatrices such as keloids, acne scars, hypertrophic scars, wrinkles, cellulite and neoplastic fibrosis which comprises intra-dermal injection of effective amounts of a pharmacologically suitable solution of the enzymes collagenase, elastase, papain, plasminogen activator, plasmin, mast cell protease or lysosomal hydrolase, individually, and one or more of such enzymes in combination with the enzyme hyaluronidase.
Inventor(s): Pinnell; Sheldon R. (Durham, NC)
Assignee: Biospecifics, NV (Curacao, AN)
Application Number:06/716,742
Patent Claims:see list of patent claims

Details for Patent 4,645,668

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Bausch & Lomb Incorporated VITRASE hyaluronidase Injection 021640 05/05/2004 See Plans and Pricing 2004-02-24
Bausch & Lomb Incorporated VITRASE hyaluronidase Injection 021640 12/02/2004 See Plans and Pricing 2004-02-24
Amphastar Pharmaceuticals, Inc. AMPHADASE hyaluronidase Injection 021665 10/26/2004 See Plans and Pricing 2004-02-24
Akorn, Inc. HYDASE hyaluronidase Injection 021716 10/25/2005 See Plans and Pricing 2004-02-24
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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