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Last Updated: September 25, 2020

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Patent: 4,645,668

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Summary for Patent: 4,645,668
Title: Method for the prevention and treatment of scars with enzymes
Abstract:The method for preventing and for treating mammalian cicatrices such as keloids, acne scars, hypertrophic scars, wrinkles, cellulite and neoplastic fibrosis which comprises intra-dermal injection of effective amounts of a pharmacologically suitable solution of the enzymes collagenase, elastase, papain, plasminogen activator, plasmin, mast cell protease or lysosomal hydrolase, individually, and one or more of such enzymes in combination with the enzyme hyaluronidase.
Inventor(s): Pinnell; Sheldon R. (Durham, NC)
Assignee: Biospecifics, NV (Curacao, AN)
Application Number:06/716,742
Patent Claims:see list of patent claims

Details for Patent 4,645,668

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bausch And Lomb VITRASE hyaluronidase INJECTABLE;INJECTION 021640 001 2004-12-21   Start Trial Biospecifics, NV (Curacao, AN) 2004-02-24 RX search
Bausch And Lomb VITRASE hyaluronidase INJECTABLE;INJECTION 021640 002 2004-12-21   Start Trial Biospecifics, NV (Curacao, AN) 2004-02-24 RX search
Amphastar Pharm AMPHADASE hyaluronidase INJECTABLE;INJECTION 021665 001 2005-11-03   Start Trial Biospecifics, NV (Curacao, AN) 2004-02-24 RX search
Akorn Inc HYDASE hyaluronidase INJECTABLE;INJECTION 021716 001 2005-10-25   Start Trial Biospecifics, NV (Curacao, AN) 2004-02-24 DISCN search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 001 1978-01-16   Start Trial Biospecifics, NV (Curacao, AN) 2004-02-24 DISCN search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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