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Patent: 4,621,053
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Summary for Patent: 4,621,053
| Title: | Process for the production of human peptide hormones |
| Abstract: | Human peptide hormones, such as insulin, growth hormone, prolactin, adrenocorticotropic hormone, placental lactogen, calcitonin, parathyroid hormone and thyroid stimulating hormone, are produced by implanting a human.times.human hybridoma lymphoblastoid cell line capable of producing the human peptide hormone in a non-human warm-blooded animal. After a period of time, the resultant tumor is extracted and disaggregated and then cultured in vitro under conditions appropriate to accumulate the human peptide hormone. The human.times.human hybridoma lymphoblastoid cell line is preferably formed by fusing parent human cells inherently capable of producing the human peptide hormone with a human lymphoblastoid line, preferably of leukemic origin. This process permits a substantial increase in the amount of human peptide hormone which can be produced. |
| Inventor(s): | Sugimoto; Kaname (Okayama, JP) |
| Assignee: | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (Okayama, JP) |
| Application Number: | 06/584,017 |
| Patent Claims: | see list of patent claims |
Details for Patent 4,621,053
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lilly | HUMULIN R | insulin recombinant human | INJECTABLE;INJECTION | 018780 | 001 | 1982-12-02 | Start Trial | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (Okayama, JP) | 2000-07-30 | RX | search | |
| Lilly | HUMULIN R KWIKPEN | insulin human | SOLUTION;SUBCUTANEOUS | 018780 | 002 | 1982-12-02 | Start Trial | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (Okayama, JP) | 2000-07-30 | RX | search | |
| Lilly | HUMULIN R | insulin human | SOLUTION;SUBCUTANEOUS | 018780 | 004 | 1982-12-02 | Start Trial | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (Okayama, JP) | 2000-07-30 | RX | search | |
| Lilly | HUMULIN R PEN | insulin recombinant human | INJECTABLE;INJECTION | 018780 | 005 | 1982-12-02 | Start Trial | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (Okayama, JP) | 2000-07-30 | RX | search | |
| Nps Pharms Inc | NATPARA | parathyroid hormone | INJECTABLE;INJECTION | 125511 | 001 | 2015-01-23 | Start Trial | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (Okayama, JP) | 2000-07-30 | RX | Orphan | search |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
International Patent Family for US Patent 4,621,053
| Country | Patent Number | Estimated Expiration |
|---|---|---|
| Switzerland | 649782 | Start Trial |
| Switzerland | 649783 | Start Trial |
| Switzerland | 650802 | Start Trial |
| Switzerland | 652745 | Start Trial |
| Switzerland | 652746 | Start Trial |
| >Country | >Patent Number | >Estimated Expiration |
