Make Better Decisions - Finding and Evaluating Generic and Branded Drug Market Entry Opportunities

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Finding and Evaluating Generic and Branded Drug Market Entry Opportunities

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Serving hundreds of leading biopharmaceutical companies globally:

McKesson
Boehringer Ingelheim
Cantor Fitzgerald
Medtronic
Healthtrust
Daiichi Sankyo

Generated: July 22, 2019

DrugPatentWatch Database Preview

Patent: 4,595,700

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Summary for Patent: 4,595,700
Title: Thiol based collagenase inhibitors
Abstract:This invention relates to compounds of the formula: ##STR1## wherein R.sub.1 represents lower alkyl, phenyl or phenyl lower alkyl; R.sub.2 and R.sub.4 represent lower alkyl; and R.sub.3 represents lower alkyl, benzyloxyalkyl, alkoxybenzyl or benzyloxybenzyl wherein the oxyalkyl or alkoxy moiety contain 1 to 6 carbon atoms; and a, b, and c represent chiral centers with optional R or S stereochemistry. These compounds inhibit collagenase and are useful in the treatment of arthritis. Also disclosed are processes for manufacture of the compounds and pharmaceutical compositions containing them.
Inventor(s): Donald; David K. (High Wycombe, GB3), Hann; Michael M. (Watlington, GB3), Saunders; John (Ickford, GB3), Wadsworth; Harry J. (High Wycombe, GB3)
Assignee: G. D. Searle & Co. (Skokie, IL)
Application Number:06/703,973
Patent Claims:see list of patent claims

Details for Patent 4,595,700

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Advance Biofactures SANTYL collagenase VIAL 101995 001 1965-06-04 ➤ Try a Free Trial G. D. Searle & Co. (Skokie, IL) ➤ Try a Free Trial RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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Serving hundreds of leading biopharmaceutical companies globally:

Harvard Business School
Deloitte
US Army
Moodys
Johnson and Johnson
McKesson

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