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Last Updated: July 24, 2021

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Patent: 4,525,456

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Summary for Patent: 4,525,456
Title: Support matrix and immobilized enzyme system
Abstract:A support matrix which immobilizes enzymes by ion exchange forces comprises a core support deposited on which is a functionalized polyethylenimine insoluble in water. Such support matrices may be prepared from a virtually limitless variety of core supports since the functionalized polyethylenimines of this invention show excellent adhesive properties even to smooth surfaces. Such support matrices are particularly useful where the enzyme to be immobilized has a rather limited inherent half-life. The functionalized polyethylenimine is a carboxylic acid amide of polyethylenimine, a sulfonic acid amide of polyethylenimine or polyalkylated polyethylenimine.
Inventor(s): Rohrbach; Ronald P. (Forest Lake, IL)
Assignee: UOP Inc. (Des Plaines, IL)
Application Number:06/439,958
Patent Claims:see list of patent claims

Details for Patent 4,525,456

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10 ⤷  Free Forever Trial UOP Inc. (Des Plaines, IL) 2039-03-29 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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