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Last Updated: September 18, 2020

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Patent: 4,446,128

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Summary for Patent: 4,446,128
Title: Antigen derivatives and processes for their preparation
Abstract:The invention relates to novel antigen derivatives comprising an antigen and at least one muramyl-peptide covalently bonded thereto, if appropriate via a spacer, to pharmaceutical preparations which contain such compounds and to their use as a vaccine. The novel antigen derivatives produce a pronounced increase in the immuno-response to the antigen, and in particular also a cell-medicated immunity under clinically acceptable conditions of administration.
Inventor(s): Baschang; Gerhard (Bettingen, CH), Dietrich; Felix M. (Basel, CH), Gisler; Roland (Binningen, CH), Hartmann; Albert (Grenzach, DE), Stanek; Jaroslav (Birsfelden, CH), Tarcsay; Lajos (Grenzach-Wyhlen, DE)
Assignee: Ciba-Geigy Corporation (Ardsley, NY)
Application Number:06/379,404
Patent Claims:see list of patent claims

Details for Patent 4,446,128

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Glaxosmithkline Biologicals Sa RABAVERT rabies vaccine KIT 103334 1 2016-12-19   Start Trial Ciba-Geigy Corporation (Ardsley, NY) 2001-05-01 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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