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Last Updated: September 30, 2020

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Patent: 4,439,521

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Summary for Patent: 4,439,521
Title: Method for producing self-reproducing mammalian pancreatic islet-like structures
Abstract:Method for producing pancreatic islet-like structures (ILS\'s) having histology and insulin-producing properties corresponding to those of fetal pancreatic islets and islets from adult animals maintained in culture. The ILS\'s are produced by culturing isolated natural pancreatic islets, pancreatic duct pieces, cell clusters consisting of mildly digested pieces of pancreas, cell tissues obtained as by-products of the culturing methods, or previously-produced ILS\'s, in attachment to a substrate.
Inventor(s): Archer; Michael C. (Mississauga, CA), Jain; Kanti (Toronto, CA)
Assignee: Ontario Cancer Institute (Toronto, CA)
Application Number:06/313,494
Patent Claims:see list of patent claims

Details for Patent 4,439,521

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bausch And Lomb VITRASE hyaluronidase INJECTABLE;INJECTION 021640 001 2004-12-21   Start Trial Ontario Cancer Institute (Toronto, CA) 2039-03-29 RX search
Bausch And Lomb VITRASE hyaluronidase INJECTABLE;INJECTION 021640 002 2004-12-21   Start Trial Ontario Cancer Institute (Toronto, CA) 2039-03-29 RX search
Amphastar Pharm AMPHADASE hyaluronidase INJECTABLE;INJECTION 021665 001 2005-11-03   Start Trial Ontario Cancer Institute (Toronto, CA) 2039-03-29 RX search
Akorn Inc HYDASE hyaluronidase INJECTABLE;INJECTION 021716 001 2005-10-25   Start Trial Ontario Cancer Institute (Toronto, CA) 2039-03-29 DISCN search
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Ontario Cancer Institute (Toronto, CA) 2039-03-29 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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