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Last Updated: December 7, 2021

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Patent: 4,425,428

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Summary for Patent: 4,425,428
Title: Novel peptide and peptolide substrates for mammalian collagenase
Abstract:Method for determination of the enzyme collagenase by reacting the enzyme with a peptide or peptolide substrate having the following amino acid sequences: R.sub.1 -Pro-Leu-Gly-Ile-Leu-Gly-Leu-R.sub.2, R.sub.1 -Gly-Pro-Leu-Gly-Ile-Leu-Gly-Ala-R.sub.2, R.sub.1 -Pro-Leu-Gly(O-Ile)-Leu-R.sub.2, R.sub.1 -Pro-Leu-Gly(O-Leu)-Leu-R.sub.2, and R.sub.1 -Pro-Leu-Gly(O-Leu)-Ala-R.sub.2, wherein R.sub.1 is H or N-protecting group, and R.sub.2 is terminal amide, carboxyl or ester group.
Inventor(s): Weingarten; Harold I. (University City, MO)
Assignee: Monsanto Company (St. Louis, MO)
Application Number:06/485,762
Patent Claims:see list of patent claims

Details for Patent 4,425,428

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Smith & Nephew, Inc. SANTYL collagenase Ointment 101995 1965-06-04 ⤷  Try it Free 2002-04-08
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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