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Last Updated: October 1, 2020

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Patent: 4,402,940

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Summary for Patent: 4,402,940
Title: Method for treating blood plasma employing a hollow fiber membrane
Abstract:This invention provides a method for treating blood plasma wherein a hollow fiber membrane which comprises at least a skin layer on one surface of the membrane and also a porous layer inside the membrane is employed. The skin layer of the membrane has micropores with average pore size of 50 to 450 A, and the membrane shows a water permeability of 80 ml/m.sup.2.hr.mmHg or more, and permeabilites for human blood plasma albumin of 85% or more and for human blood plasma immunoglobulin G(IgG) of 80% or more, and a rate of inhibition against human blood plasma immunoglobulin M(IgM) of 40% or more. Use of the above mentioned hollow fiber membrane, which makes it possible to selectively remove immune complex, rheumatoid factors, etc., without decrease in levels of immunological functions, brings excellent effects on therapy of autoimmune diseases.
Inventor(s): Nose; Yukihiko (Cleveland, OH), Kayashima; Koji (Mayfield, OH), Sueoka; Akinori (South Euclid, OH), Asanuma; Yoshihiro (Sendai, JP), Shinagawa; Shigeru (Cleveland, OH), Smith; James (Cleveland, OH), Werynski; Andrej (Warsaw, PL), Malchesky; Paul S. (Painesvilla Township, Lake County, OH)
Assignee: Kuraray Co., Ltd. (Kurashiki, JP)
Application Number:06/418,551
Patent Claims:see list of patent claims

Details for Patent 4,402,940

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Octapharma Usa Inc CUTAQUIG immunoglobulin g SOLUTION 125668 1 2019-05-03   Start Trial Kuraray Co., Ltd. (Kurashiki, JP) 2002-03-12 search
Bpl ALBUMINEX albumin human SOLUTION 125644 1 2020-05-27   Start Trial Kuraray Co., Ltd. (Kurashiki, JP) 2002-03-12 search
Kedrion S.p.a KEDBUMIN albumin (human) INJECTION, SOLUTION 125384 1 2011-09-15   Start Trial Kuraray Co., Ltd. (Kurashiki, JP) 2002-03-12 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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