Last Updated: May 14, 2026

Patent: 4,374,926

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Summary for Patent: 4,374,926

Title:	Method for the production of improved chymopapain
Abstract:	A method of preparing a purified proteolytically active chymopapain from crude chymopapain extracts by the use of exchange resin absorption purification techniques is provided. The purified chymopapain is characterized by relative freedom from proteolytically inactive, colored and/or toxic components and by its failure to form a precipitate with barium chloride test solution (U.S.P.) under acid conditions.
Inventor(s):	Stern; Ivan J. (Chicago, IL)
Assignee:	Smith Laboratories, Inc. (Northbrook, IL)
Application Number:	06/263,196
Patent Claims:	see list of patent claims

Details for Patent 4,374,926

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Discure Medical, Llc	CHYMODIACTIN	chymopapain	For Injection	018663	November 10, 1982	⤷ Start Trial	2001-05-13
Discure Medical, Llc	CHYMODIACTIN	chymopapain	For Injection	018663	August 21, 1984	⤷ Start Trial	2001-05-13
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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