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Last Updated: September 22, 2020

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Patent: 4,371,462

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Summary for Patent: 4,371,462
Title: Method for purification of anterior pituitary hormones
Abstract:Mixtures containing an anterior pituitary hormone such as growth hormone or prolactin are treated to produce relatively pure hormone by a process comprising eluting the mixture through an ion-exchange column followed by fractionation of the eluent on an isoelectric focusing column. Fractions at the isoelectric point of the specific anterior pituitary hormone can be pooled, dialyzed with sterile water, and then lyophilized. The identity of the resulting product can be confirmed by electrophoretic analysis on sodium dodecylsulfate gel, immunodiffusion on an Ouchterlony plate, or both.
Inventor(s): Hecht; Randy I. (Rockville, MD)
Assignee: Genex Corporation (Rockville, MD)
Application Number:06/341,216
Patent Claims:see list of patent claims

Details for Patent 4,371,462

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 001 2006-05-25   Start Trial Genex Corporation (Rockville, MD) 2039-09-23 search
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 1 2006-05-25   Start Trial Genex Corporation (Rockville, MD) 2039-09-23 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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