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Last Updated: September 30, 2020

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Patent: 4,337,240

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Summary for Patent: 4,337,240
Title: Denatured albumin complexes for radioscintigraphic imaging and evaluation of reticuloendothelial systems
Abstract:Small sized material (less than 0.2 .mu.m, preferably less than 0.1 .mu.m) comprising a complex of (1) denatured albumin, particularly human serum albumin and (2) a metal reducing agent, particularly a stannous reducing agent, preferably formed in the presence of a stabilizing ligand, which complex, when labelled with technetium-99m provides an excellent agent for imaging or otherwise evaluating reticuloendothelial systems (RES) and/or components thereof, particularly the bone marrow, liver and/or lymphatic system; methods of making and using the same; a complex (physical or chemical) of technetium-99m with such materials and methods of using such latter complex.
Inventor(s): Saklad; Eugene L. (Sudbury, MA)
Assignee: New England Nuclear Corporation (Boston, MA)
Application Number:06/018,312
Patent Claims:see list of patent claims

Details for Patent 4,337,240

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Grifols Usa, Llc PLASBUMIN albumin (human) SOLUTION 101138 1 1994-09-26   Start Trial New England Nuclear Corporation (Boston, MA) 1998-04-20 search
Baxalta Us Inc. FLEXBUMIN albumin human INJECTION, SOLUTION 101452 1 2014-07-31   Start Trial New England Nuclear Corporation (Boston, MA) 1998-04-20 search
Csl Behring Ag ALBURX albumin (human) SOLUTION 102366 1 2009-01-06   Start Trial New England Nuclear Corporation (Boston, MA) 1998-04-20 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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