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Last Updated: September 24, 2020

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Patent: 4,246,351

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Summary for Patent: 4,246,351
Title: Protein adsorbent
Abstract:A novel protein adsorbent consisting essentially of a porous copolymer obtained by copolymerizing a monomer mixture comprising at least one cyano group-containing monomer and at least one cross-linkable monomer, said copolymer having an average pore diameter (d) of from 40 A to 9,000 A and a total pore volume of from 0.05.sqroot.X ml to 1.5.sqroot.X ml per gram of the copolymer in a dry state, in which X designates the weight proportion of said cross-linkable monomer expressed in terms of the percent by weight based on the total monomers. The present porous copolymer adsorbent has a remarkably high protein adsorbing capacity. The adorbent can advantageously be used for various purposes such as purification and separation of proteins, and removal of proteins. Copolymer-protein composites obtained by adsorption of proteins on the present porous copolymer also are industrially useful and have a wide variety of applications.
Inventor(s): Miyake; Tetsuya (Tokyo, JP), Takeda; Kunihiko (Yokohama, JP), Ikeda; Akihiko (Yokohama, JP), Mizuno; Masayuki (Nobeoka, JP)
Assignee: Asahi Kasei Kogyo Kabushiki Kaisha (Osaka, JP)
Application Number:06/088,927
Patent Claims:see list of patent claims

Details for Patent 4,246,351

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Grifols Usa, Llc PLASBUMIN albumin (human) SOLUTION 101138 1 1994-09-26   Start Trial Asahi Kasei Kogyo Kabushiki Kaisha (Osaka, JP) 1998-01-20 search
Baxalta Us Inc. FLEXBUMIN albumin human INJECTION, SOLUTION 101452 1 2014-07-31   Start Trial Asahi Kasei Kogyo Kabushiki Kaisha (Osaka, JP) 1998-01-20 search
Csl Behring Ag ALBURX albumin (human) SOLUTION 102366 1 2009-01-06   Start Trial Asahi Kasei Kogyo Kabushiki Kaisha (Osaka, JP) 1998-01-20 search
Grifols Usa, Llc ALBUTEIN albumin (human) INJECTION, SOLUTION 102478 1 2019-12-15   Start Trial Asahi Kasei Kogyo Kabushiki Kaisha (Osaka, JP) 1998-01-20 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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