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Generated: December 12, 2018

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Patent: 4,237,229

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Summary for Patent: 4,237,229
Title: Immobilization of biological material with polyurethane polymers
Abstract:A process for immobilizing a biological material which can be a protein, a coenzyme having at least one primary or secondary amino group per molecule, an admixture of said coenzyme and an enzyme which is mediated by said coenzyme, or an antibiotic having at least one primary or secondary amino group per molecule, wherein the biological material is contacted with an excess of an isocyanate-capped liquid polyurethane prepolymer in the absence of water, and the resulting mixture is cured by contacting it with a curing agent to cure the prepolymer and to immobilize the biological material. The resulting mixture can be cured under foam-forming conditions or under nonfoam-forming conditions. The resulting mixture can be formed into a predetermined shape before or during curing or coated onto a surface before or during curing.
Inventor(s): Hartdegen; Frank J. (Columbia, MD), Swann; Wayne E. (Pasadena, MD)
Assignee: W. R. Grace & Co. (New York, NY)
Application Number:05/849,990
Patent Claim Types:
see list of patent claims
Compound; Process;

Details for Patent 4,237,229

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10 ➤ Sign Up W. R. Grace & Co. (New York, NY) ➤ Sign Up RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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