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Last Updated: September 26, 2022

Patent: 4,237,229


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Summary for Patent: 4,237,229
Title: Immobilization of biological material with polyurethane polymers
Abstract:A process for immobilizing a biological material which can be a protein, a coenzyme having at least one primary or secondary amino group per molecule, an admixture of said coenzyme and an enzyme which is mediated by said coenzyme, or an antibiotic having at least one primary or secondary amino group per molecule, wherein the biological material is contacted with an excess of an isocyanate-capped liquid polyurethane prepolymer in the absence of water, and the resulting mixture is cured by contacting it with a curing agent to cure the prepolymer and to immobilize the biological material. The resulting mixture can be cured under foam-forming conditions or under nonfoam-forming conditions. The resulting mixture can be formed into a predetermined shape before or during curing or coated onto a surface before or during curing.
Inventor(s): Hartdegen; Frank J. (Columbia, MD), Swann; Wayne E. (Pasadena, MD)
Assignee: W. R. Grace & Co. (New York, NY)
Application Number:05/849,990
Patent Claims:see list of patent claims

Details for Patent 4,237,229

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Recordati Rare Diseases, Inc. ELSPAR asparaginase For Injection 101063 01/10/1978 See Plans and Pricing 1995-12-24
Csl Behring Ag CARIMUNE, CARIMUNE NF, PANGLOBULIN, SANDOGLOBULIN immune globulin intravenous (human) For Injection 102367 07/27/2000 See Plans and Pricing 1995-12-24
Csl Behring Ag PRIVIGEN immune globulin intravenous (human), 10% liquid Injection 125201 07/26/2007 See Plans and Pricing 1995-12-24
Csl Behring Ag PRIVIGEN immune globulin intravenous (human), 10% liquid Injection 125201 10/02/2009 See Plans and Pricing 1995-12-24
Csl Behring Ag PRIVIGEN immune globulin intravenous (human), 10% liquid Injection 125201 02/07/2013 See Plans and Pricing 1995-12-24
Bio Products Laboratory GAMMAPLEX immune globulin intravenous (human) Injection 125329 09/17/2009 See Plans and Pricing 1995-12-24
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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