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Last Updated: September 22, 2020

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Patent: 4,226,847

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Summary for Patent: 4,226,847
Title: Latex polymer sensitized with steroid-serum albumin conjugate, preparation and test therewith
Abstract:Latex reagents for quantitative assay of a variety of steroid hormones or metabolites thereof which are contained in body fluid or excreted fluid of human beings comprise latex particles which are immunologically sensitized with a conjugate selected from a variety of steroid-serum albumin conjugates in which the steroid to be detected is bonded to serum albumin in a very small ratio ranging from 0.5 to 7 molecules per 1 molecule of the serum albumin used. Sensitization of latex particles with such a conjugate is performed using a limited amount dependent on the bonding ratio of steroid molecules per molecule of serum albumin in the conjugate and the particle size of the latex used. The latex reagents show very high sensitivity amounting to 0.2-0.04 nmole steroid equivalent/ml.
Inventor(s): Ogasa; Katsuhiro (Yokohama, JP), Kuboyama; Morio (Tokyo, JP), Saito; Minoru (Komae, JP), Kudo; Tsutomu (Kawasaki, JP), Harada; Yoshitsugu (Yokohama, JP), Kawashiri; Akio (Fujimi, JP), Takahashi; Eiji (Tokyo, JP)
Assignee: Morinaga Milk Industry Co., Ltd. (Tokyo, JP)
Application Number:05/917,254
Patent Claims:see list of patent claims

Details for Patent 4,226,847

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Grifols Usa, Llc PLASBUMIN albumin (human) SOLUTION 101138 1 1994-09-26   Start Trial Morinaga Milk Industry Co., Ltd. (Tokyo, JP) 1997-10-07 search
Baxalta Us Inc. FLEXBUMIN albumin human INJECTION, SOLUTION 101452 1 2014-07-31   Start Trial Morinaga Milk Industry Co., Ltd. (Tokyo, JP) 1997-10-07 search
Csl Behring Ag ALBURX albumin (human) SOLUTION 102366 1 2009-01-06   Start Trial Morinaga Milk Industry Co., Ltd. (Tokyo, JP) 1997-10-07 search
Grifols Usa, Llc ALBUTEIN albumin (human) INJECTION, SOLUTION 102478 1 2019-12-15   Start Trial Morinaga Milk Industry Co., Ltd. (Tokyo, JP) 1997-10-07 search
Grifols Usa, Llc HUMAN ALBUMIN GRIFOLS albumin (human) SOLUTION 103352 1 2003-06-11   Start Trial Morinaga Milk Industry Co., Ltd. (Tokyo, JP) 1997-10-07 search
Csl Behring Llc ALBUMINAR-25 albumin (human) SOLUTION 103955 1 2009-01-06   Start Trial Morinaga Milk Industry Co., Ltd. (Tokyo, JP) 1997-10-07 search
Octapharma Usa Inc ALBUMIN (HUMAN) albumin human SOLUTION 125154 1 2006-10-17   Start Trial Morinaga Milk Industry Co., Ltd. (Tokyo, JP) 1997-10-07 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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