Patent: 10,519,479

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Summary for Patent: 10,519,479

Title:	Methods for modifying glycosylation using manganese
Abstract:	The present invention relates to a cell culture method for adjusting the proportion of G0, G1, G2, and high-mannose galactosylation variants in a population of a recombinant protein produced by a culture of cells in a cell culture medium by supplementing the cell culture medium with manganese at one or more days of the cell culture method duration.
Inventor(s):	Solacroup; Thomas (Blonay, CH), Stettler; Matthieu (Vucherens, CH), Jordan; Martin (Ecublens, CH), Broly; Herve (Chatel-St Denis, CH)
Assignee:	ARES TRADING S.A. (Aubonne, CH)
Application Number:	15/457,624
Patent Claims:	see list of patent claims

Details for Patent 10,519,479

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Janssen Biotech, Inc.	REMICADE	infliximab	For Injection	103772	08/24/1998	⤷ Try a Trial	2040-01-24
Immunex Corporation	ENBREL	etanercept	For Injection	103795	11/02/1998	⤷ Try a Trial	2040-01-24
Immunex Corporation	ENBREL	etanercept	For Injection	103795	05/27/1999	⤷ Try a Trial	2040-01-24
Immunex Corporation	ENBREL	etanercept	Injection	103795	09/27/2004	⤷ Try a Trial	2040-01-24
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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