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Last Updated: September 28, 2020

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Patent: 10,519,479

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Summary for Patent: 10,519,479
Title:Methods for modifying glycosylation using manganese
Abstract: The present invention relates to a cell culture method for adjusting the proportion of G0, G1, G2, and high-mannose galactosylation variants in a population of a recombinant protein produced by a culture of cells in a cell culture medium by supplementing the cell culture medium with manganese at one or more days of the cell culture method duration.
Inventor(s): Solacroup; Thomas (Blonay, CH), Stettler; Matthieu (Vucherens, CH), Jordan; Martin (Ecublens, CH), Broly; Herve (Chatel-St Denis, CH)
Assignee: ARES TRADING S.A. (Aubonne, CH)
Application Number:15/457,624
Patent Claims:see list of patent claims

Details for Patent 10,519,479

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Centocor Inc REMICADE infliximab VIAL 103772 001 1998-08-24   Start Trial ARES TRADING S.A. (Aubonne, CH) 2040-01-24 RX Orphan search
Immunex ENBREL etanercept VIAL; SUBCUTANEOUS 103795 001 1998-11-02   Start Trial ARES TRADING S.A. (Aubonne, CH) 2040-01-24 RX Orphan search
Immunex ENBREL etanercept SYRINGE 103795 002 1998-11-02   Start Trial ARES TRADING S.A. (Aubonne, CH) 2040-01-24 RX Orphan search
Abbvie Inc HUMIRA adalimumab SYRINGE 125057 001 2002-12-31   Start Trial ARES TRADING S.A. (Aubonne, CH) 2040-01-24 RX search
Abbvie Inc HUMIRA adalimumab VIAL 125057 002 2002-12-31   Start Trial ARES TRADING S.A. (Aubonne, CH) 2040-01-24 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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