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Last Updated: June 3, 2023

Patent: 10,519,479

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Summary for Patent: 10,519,479
Title:Methods for modifying glycosylation using manganese
Abstract: The present invention relates to a cell culture method for adjusting the proportion of G0, G1, G2, and high-mannose galactosylation variants in a population of a recombinant protein produced by a culture of cells in a cell culture medium by supplementing the cell culture medium with manganese at one or more days of the cell culture method duration.
Inventor(s): Solacroup; Thomas (Blonay, CH), Stettler; Matthieu (Vucherens, CH), Jordan; Martin (Ecublens, CH), Broly; Herve (Chatel-St Denis, CH)
Assignee: ARES TRADING S.A. (Aubonne, CH)
Application Number:15/457,624
Patent Claims:see list of patent claims

Details for Patent 10,519,479

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Janssen Biotech, Inc. REMICADE infliximab For Injection 103772 08/24/1998 ⤷  Try a Trial 2040-01-24
Immunex Corporation ENBREL etanercept For Injection 103795 11/02/1998 ⤷  Try a Trial 2040-01-24
Immunex Corporation ENBREL etanercept For Injection 103795 05/27/1999 ⤷  Try a Trial 2040-01-24
Immunex Corporation ENBREL etanercept Injection 103795 09/27/2004 ⤷  Try a Trial 2040-01-24
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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