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Last Updated: September 27, 2020

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Patent: 10,450,365

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Summary for Patent: 10,450,365
Title:Recombinant human antibodies for therapy and prevention of polyomavirus-related diseases
Abstract: Provided are novel human-derived antibodies specifically recognizing polyomavirus polypeptides, preferably capable of binding to polyomaviruses of the type of JC virus (JCV) and/or BK virus (BKV) as well as methods related thereto. Furthermore, assays and kits related to antibodies specific for polyomaviruses, polyomavirus VP1 and or polyomavirus VP1 Virus-Like Particles (VLPs), preferably of the type of JCV and/or BKV, are disclosed. The human-derived antibodies as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for polyomavirus targeted immunotherapy and diagnostics.
Inventor(s): Grimm; Jan (Dubendorf, CH), Martin; Roland (Zurich, CH), Combaluzier; Benoit (Urdorf, CH), Jelcic; Ivan (Zurich, CH)
Assignee: Neurimmune Holding AG (Schlieren, CH) University of Zurich (Zurich, CH)
Application Number:15/678,965
Patent Claims:see list of patent claims

Details for Patent 10,450,365

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 001 1997-11-26   Start Trial Neurimmune Holding AG (Schlieren, CH) University of Zurich (Zurich, CH) 2032-12-31 RX search
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 002 1997-11-26   Start Trial Neurimmune Holding AG (Schlieren, CH) University of Zurich (Zurich, CH) 2032-12-31 RX search
Centocor Inc REMICADE infliximab VIAL 103772 001 1998-08-24   Start Trial Neurimmune Holding AG (Schlieren, CH) University of Zurich (Zurich, CH) 2032-12-31 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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