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Last Updated: December 5, 2021

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Patent: 10,450,365

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Summary for Patent: 10,450,365
Title:Recombinant human antibodies for therapy and prevention of polyomavirus-related diseases
Abstract: Provided are novel human-derived antibodies specifically recognizing polyomavirus polypeptides, preferably capable of binding to polyomaviruses of the type of JC virus (JCV) and/or BK virus (BKV) as well as methods related thereto. Furthermore, assays and kits related to antibodies specific for polyomaviruses, polyomavirus VP1 and or polyomavirus VP1 Virus-Like Particles (VLPs), preferably of the type of JCV and/or BKV, are disclosed. The human-derived antibodies as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for polyomavirus targeted immunotherapy and diagnostics.
Inventor(s): Grimm; Jan (Dubendorf, CH), Martin; Roland (Zurich, CH), Combaluzier; Benoit (Urdorf, CH), Jelcic; Ivan (Zurich, CH)
Assignee: Neurimmune Holding AG (Schlieren, CH) University of Zurich (Zurich, CH)
Application Number:15/678,965
Patent Claims:see list of patent claims

Details for Patent 10,450,365

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. RITUXAN rituximab Injection 103705 1997-11-26 ⤷  Try it Free 2032-12-31
Janssen Biotech, Inc. REMICADE infliximab For Injection 103772 1998-08-24 ⤷  Try it Free 2032-12-31
Genzyme Corporation CAMPATH alemtuzumab Injection 103948 2001-05-07 ⤷  Try it Free 2032-12-31
Genzyme Corporation LEMTRADA alemtuzumab Injection 103948 2014-11-14 ⤷  Try it Free 2032-12-31
Genzyme Corporation CAMPATH alemtuzumab Injection 103948 2004-10-12 ⤷  Try it Free 2032-12-31
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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