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Last Updated: November 29, 2021

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Patent: 10,420,723

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Summary for Patent: 10,420,723
Title:Milk-derived microvesicle compositions and related methods
Abstract: A composition is provided that comprises a therapeutic agent encapsulated by a milk-derived microvesicle. The compositions can include therapeutic agents such as phytochemical agents or chemotherapeutic agents, while the milk-derived microvesicle can be derived from raw milk or colostrum. Further provided are methods for isolating a microvesicle that includes the steps of obtaining an amount of milk, and subjecting the milk to a series of sequential centrifugations configured to yield greater than about 300 mg of microvesicle protein per 100 ml of milk. Methods of modifying an immune response and treating a cancer in which a milk-derived microvesicle composition is administered are also provided.
Inventor(s): Gupta; Ramesh C. (Prospect, KY), Munagala; Radha (Louisville, KY), Aqil; Farrukh (Louisville, KY), Jeyabalan; Jeyaprakash (Louisville, KY)
Assignee: University of Louisville Research Foundation, Inc. (Louisville, KY)
Application Number:15/910,322
Patent Claims:see list of patent claims

Details for Patent 10,420,723

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 1998-09-25 ⤷  Try it Free 2033-02-26
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 2017-02-10 ⤷  Try it Free 2033-02-26
Genentech, Inc. HERCEPTIN HYLECTA trastuzumab and hyaluronidase-oysk Injection 761106 2019-02-28 ⤷  Try it Free 2033-02-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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