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Last Updated: September 27, 2020

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Patent: 10,391,166

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Summary for Patent: 10,391,166
Title:Short oligonucleotides as vaccine adjuvants and therapeutic agents
Abstract: The invention provides a method of treating a microbial infection in a subject and a method of improving an immune system response in a subject against a disease, condition, infection, or virus thereof, by administering an effective amount of a nucleoside, short oligonucleotide compound or an analog thereof, or a pharmaceutically acceptable salt, racemate, enantiomer, diastereomer, geometric isomer, or tautomer thereof. In addition, the invention provides methods for treating or preventing a viral infection, bacterial infection, parasitic infection, or fungal infection in a subject (such as, a human). The compounds of the invention include, for example, di-, and trinucleotide compounds as provided herein. The compounds of the invention are useful for different therapeutic applications including, such as, prophylactics and therapeutics. The invention also provides design and synthesis of a compound that is useful for various therapeutic applications as mentioned herein.
Inventor(s): Iyer; Radhakrishnan P. (Shrewsbury, MA)
Application Number:14/767,113
Patent Claims:see list of patent claims

Details for Patent 10,391,166

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Organon Usa Inc. BCG VACCINE bacillus calmette-guerin substrain tice live antigen INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 103050 1 1989-06-21   Start Trial SPRING BREAK PHARMACEUTICALS, INC. (Milford, MA) 2033-02-18 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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