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Last Updated: December 1, 2021

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Patent: 10,385,139

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Summary for Patent: 10,385,139
Title:Murine, chimeric, humanized or human anti-TNF-alpha antibodies
Abstract: The present invention concerns compositions and methods of use of bispecific antibodies comprising at least one anti-TNF-.alpha. antibody or antigen-binding fragment thereof and at least one anti-IL-6 antibody or antigen-binding fragment thereof. Preferably, the bispecific antibody is in the form of a DNL.RTM. complex. The anti-TNF-.alpha. or anti-IL-6 antibodies may comprise specific CDR sequences disclosed herein. The compositions and methods are of use to treat autoimmune disease, immune system dysfunction or inflammatory disease, as disclosed herein.
Inventor(s): Goldenberg; David M. (Mendham, NJ), Li; Rongxiu (Parsippany, NJ), Chang; Chien-Hsing (Downingtown, PA)
Assignee: IBC Pharmaceuticals, Inc. (Morris Plains, NJ)
Application Number:15/897,847
Patent Claims:see list of patent claims

Details for Patent 10,385,139

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Recordati Rare Diseases, Inc. ELSPAR asparaginase For Injection 101063 1978-01-10 ⤷  Try it Free 2033-11-01
Nps Pharmaceuticals, Inc. NATPARA parathyroid hormone For Injection 125511 2015-01-23 ⤷  Try it Free 2033-11-01
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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