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Last Updated: September 28, 2020

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Patent: 10,385,131

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Summary for Patent: 10,385,131
Title:Combination therapies of HDAC inhibitors and PD-L1 inhibitors
Abstract: Provided herein are combinations that include an HDACi and a PD-L1 inhibitor that are useful for treating cancer, including cancer resistant to PD-1 inhibitors.
Inventor(s): Bissonnette; Reid P. (Carlsbad, CA), Rolland; Alain (San Diego, CA), Gillings; Mireille (Winchester CDP, NV)
Assignee: HUYA Bioscience International, LLC (San Diego, CA)
Application Number:15/592,929
Patent Claims:see list of patent claims

Details for Patent 10,385,131

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech Inc TECENTRIQ atezolizumab INJECTABLE;INJECTION 761034 001 2017-04-17   Start Trial HUYA Bioscience International, LLC (San Diego, CA) 2036-05-11 RX Orphan search
Genentech Inc TECENTRIQ atezolizumab INJECTABLE; INJECTION 761041 001 2016-10-18   Start Trial HUYA Bioscience International, LLC (San Diego, CA) 2036-05-11 RX search
Emd Serono Inc BAVENCIO avelumab INJECTABLE;INJECTION 761049 001 2017-04-25   Start Trial HUYA Bioscience International, LLC (San Diego, CA) 2036-05-11 RX Orphan search
Astrazeneca Uk Ltd IMFINZI durvalumab INJECTABLE;INJECTION 761069 001 2017-05-01   Start Trial HUYA Bioscience International, LLC (San Diego, CA) 2036-05-11 RX search
Emd Serono Inc BAVENCIO avelumab INJECTABLE;INTRAVENOUS 761078 001 2017-05-09   Start Trial HUYA Bioscience International, LLC (San Diego, CA) 2036-05-11 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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