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Last Updated: September 24, 2020

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Patent: 10,385,130

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Summary for Patent: 10,385,130
Title:Combination therapies of HDAC inhibitors and PD-1 inhibitors
Abstract: Provided herein are combinations that include an HDACi and a PD-1 inhibitor that are useful for treating cancer, including reducing and/or preventing cancer metastasis. The combination is also useful for treating cancer that has been previously treated with a PD-L1 inhibitor.
Inventor(s): Bissonnette; Reid P. (Carlsbad, CA), Rolland; Alain (San Diego, CA), Gillings; Mireille (Winchester CDP, NV)
Assignee: HUYA Bioscience International, LLC (San Diego, CA)
Application Number:15/592,988
Patent Claims:see list of patent claims

Details for Patent 10,385,130

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck Sharp Dohme KEYTRUDA pembrolizumab POWDER, FOR INJECTION SOLUTION, LYOPHILIZED POWDER 125514 001 2014-09-04   Start Trial HUYA Bioscience International, LLC (San Diego, CA) 2036-05-11 RX Orphan search
Bristol Myers Squibb OPDIVO nivolumab INJECTABLE;INJECTION 125527 001 2015-03-04   Start Trial HUYA Bioscience International, LLC (San Diego, CA) 2036-05-11 RX search
Bristol Myers Squibb OPDIVO nivolumab INJECTABLE;INJECTION 125527 002 2015-03-04   Start Trial HUYA Bioscience International, LLC (San Diego, CA) 2036-05-11 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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