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Last Updated: December 6, 2021

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Patent: 10,385,130

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Summary for Patent: 10,385,130
Title:Combination therapies of HDAC inhibitors and PD-1 inhibitors
Abstract: Provided herein are combinations that include an HDACi and a PD-1 inhibitor that are useful for treating cancer, including reducing and/or preventing cancer metastasis. The combination is also useful for treating cancer that has been previously treated with a PD-L1 inhibitor.
Inventor(s): Bissonnette; Reid P. (Carlsbad, CA), Rolland; Alain (San Diego, CA), Gillings; Mireille (Winchester CDP, NV)
Assignee: HUYA Bioscience International, LLC (San Diego, CA)
Application Number:15/592,988
Patent Claims:see list of patent claims

Details for Patent 10,385,130

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. KEYTRUDA pembrolizumab For Injection 125514 2014-09-04 ⤷  Free Forever Trial 2036-05-11
Merck Sharp & Dohme Corp. KEYTRUDA pembrolizumab Injection 125514 2015-01-15 ⤷  Free Forever Trial 2036-05-11
Bristol-myers Squibb Company OPDIVO nivolumab Injection 125554 2014-12-22 ⤷  Free Forever Trial 2036-05-11
Bristol-myers Squibb Company OPDIVO nivolumab Injection 125554 2017-10-04 ⤷  Free Forever Trial 2036-05-11
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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