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Last Updated: July 2, 2020

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Patent: 10,383,954

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Summary for Patent: 10,383,954
Title:Methods of inducing responsiveness to anti-angiogenic agent
Abstract: The invention provides methods of inducing or improving responsiveness to a VEGF antagonist to a subject or a subject population comprising administering an adenovirus comprising a nucleic acid construct comprising a F AS-chimera gene operably linked to an endothelial cell-specific promoter and administering the VEGF antagonist.
Inventor(s): Leubitz; Andrea Rachel (Efrat, IL), Sher; Naamit (Rechovot, IL), Feige; Erez (Hemed, IL), Breitbart; Eyal (Hashmonaim, IL)
Assignee: Vascular Biogenics Ltd. (Modi\'in, IL)
Application Number:15/607,083
Patent Claims:see list of patent claims

Details for Patent 10,383,954

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Eli Lilly And Co CYRAMZA ramucirumab INJECTABLE;INJECTION 125477 002 2014-04-21   Start Trial Vascular Biogenics Ltd. (Modi\'in, IL) 2033-02-04 RX search
Eli Lilly And Co CYRAMZA ramucirumab INJECTABLE;INJECTION 125477 001 2014-04-21   Start Trial Vascular Biogenics Ltd. (Modi\'in, IL) 2033-02-04 RX search
Regeneron Pharmaceuticals EYLEA aflibercept INJECTABLE; INJECTION 125387 001 2011-11-18   Start Trial Vascular Biogenics Ltd. (Modi\'in, IL) 2033-02-04 RX search
Genentech LUCENTIS ranibizumab INJECTABLE; INJECTION 125156 001 2006-06-30   Start Trial Vascular Biogenics Ltd. (Modi\'in, IL) 2033-02-04 RX search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26   Start Trial Vascular Biogenics Ltd. (Modi\'in, IL) 2033-02-04 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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