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Last Updated: September 23, 2020

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Patent: 10,370,346

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Summary for Patent: 10,370,346
Title:KDM1A inhibitors for the treatment of disease
Abstract: Disclosed herein are new compounds and compositions and their application as pharmaceuticals for the treatment of diseases. Methods of inhibition of KDM1A, methods of increasing gamma globin gene expression, and methods to induce differentiation of cancer cells in a human or animal subject are also provided for the treatment of diseases such as acute myelogenous leukemia.
Inventor(s): McCall; John M. (Boca Grande, FL), Rienhoff, Jr.; Hugh Y. (San Carlos, CA), Clare; Michael (Skokie, IL)
Assignee: Imago Biosciences, Inc. (San Carlos, CA)
Application Number:15/667,166
Patent Claims:see list of patent claims

Details for Patent 10,370,346

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck Sharp Dohme KEYTRUDA pembrolizumab POWDER, FOR INJECTION SOLUTION, LYOPHILIZED POWDER 125514 001 2014-09-04   Start Trial Imago Biosciences, Inc. (San Carlos, CA) 2033-08-06 RX Orphan search
Bristol Myers Squibb OPDIVO nivolumab INJECTABLE;INJECTION 125527 001 2015-03-04   Start Trial Imago Biosciences, Inc. (San Carlos, CA) 2033-08-06 RX search
Bristol Myers Squibb OPDIVO nivolumab INJECTABLE;INJECTION 125527 002 2015-03-04   Start Trial Imago Biosciences, Inc. (San Carlos, CA) 2033-08-06 RX search
Bristol Myers Squibb OPDIVO nivolumab INJECTABLE;INJECTION 125554 001 2015-11-23   Start Trial Imago Biosciences, Inc. (San Carlos, CA) 2033-08-06 RX Orphan search
Genentech Inc TECENTRIQ atezolizumab INJECTABLE;INJECTION 761034 001 2017-04-17   Start Trial Imago Biosciences, Inc. (San Carlos, CA) 2033-08-06 RX Orphan search
Genentech Inc TECENTRIQ atezolizumab INJECTABLE; INJECTION 761041 001 2016-10-18   Start Trial Imago Biosciences, Inc. (San Carlos, CA) 2033-08-06 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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