Patent: 10,345,315

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Summary for Patent: 10,345,315

Title:	IGFBP7 for diagnosing diastolic dysfunction
Abstract:	Disclosed herein is a method for diagnosing and/or grading diastolic dysfunction or at least one structural or functional abnormality associated with diastolic dysfunction. The method involves measuring the level of IGFBP7 (Insulin like growth factor binding protein 7) and, optionally, the level of at least one further marker in a patient suffering from heart failure, and comparing the level to a reference level. Also disclosed is a method of monitoring diastolic function in a patient suffering from heart failure, and kits and devices for performing the method.
Inventor(s):	Karl; Johann (Peissenberg, DE), Wienhues-Thelen; Ursula-Henrike (Krailling, DE), Block; Dirk (Bichl, DE), Zaugg; Christian (Rheinfelden, CH), Brunner; Hans-Peter (Muenchenstein, CH), Januzzi; James (Wellesley, MA), Ziegler; Andre (Laeufelfingen, CH), Braz; Julian (Greenwood, IN), Dieterle; Thomas (Freiburg, DE), Kaiser; Edelgard (Huenenberg See, CH)
Assignee:	Roche Diagnostics Operations, Inc. (Indianapolis, IN)
Application Number:	15/274,533
Patent Claims:	see list of patent claims

Details for Patent 10,345,315

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Number	Approval Date	Patent No.	Assignee	Estimated Patent Expiration	Status	Orphan	Source
Biovitrum Ab	KINERET	anakinra	VIAL; SUBCUTANEOUS	103950	001	2001-11-14	Start Trial	Roche Diagnostics Operations, Inc. (Indianapolis, IN)	2034-03-26	RX		search
Biovitrum Ab	KINERET	anakinra	VIAL; SUBCUTANEOUS	103950	002	2001-11-14	Start Trial	Roche Diagnostics Operations, Inc. (Indianapolis, IN)	2034-03-26	RX		search
Biovitrum Ab	KINERET	anakinra	VIAL; SUBCUTANEOUS	103950	003	2001-11-14	Start Trial	Roche Diagnostics Operations, Inc. (Indianapolis, IN)	2034-03-26	RX		search
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Number	>Approval Date	>Patent No.	>Assignee	>Estimated Patent Expiration	>Status	>Orphan	>Source

International Patent Family for US Patent 10,345,315

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Country	Patent Number	Publication Date
Canada	2943662	Oct 01, 2015
Canada	2943662	Sep 24, 2019
China	106461672	Feb 22, 2017
China	106461672	Sep 04, 2018
European Patent Office	2924438	Apr 18, 2018
>Country	>Patent Number	>Publication Date

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