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Patent: 10,345,315
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Summary for Patent: 10,345,315
| Title: | IGFBP7 for diagnosing diastolic dysfunction |
| Abstract: | Disclosed herein is a method for diagnosing and/or grading diastolic dysfunction or at least one structural or functional abnormality associated with diastolic dysfunction. The method involves measuring the level of IGFBP7 (Insulin like growth factor binding protein 7) and, optionally, the level of at least one further marker in a patient suffering from heart failure, and comparing the level to a reference level. Also disclosed is a method of monitoring diastolic function in a patient suffering from heart failure, and kits and devices for performing the method. |
| Inventor(s): | Karl; Johann (Peissenberg, DE), Wienhues-Thelen; Ursula-Henrike (Krailling, DE), Block; Dirk (Bichl, DE), Zaugg; Christian (Rheinfelden, CH), Brunner; Hans-Peter (Muenchenstein, CH), Januzzi; James (Wellesley, MA), Ziegler; Andre (Laeufelfingen, CH), Braz; Julian (Greenwood, IN), Dieterle; Thomas (Freiburg, DE), Kaiser; Edelgard (Huenenberg See, CH) |
| Assignee: | Roche Diagnostics Operations, Inc. (Indianapolis, IN) |
| Application Number: | 15/274,533 |
| Patent Claims: | see list of patent claims |
Details for Patent 10,345,315
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Biovitrum Ab | KINERET | anakinra | VIAL; SUBCUTANEOUS | 103950 | 003 | 2001-11-14 | Start Trial | Roche Diagnostics Operations, Inc. (Indianapolis, IN) | 2034-03-26 | RX | search | |
| Biovitrum Ab | KINERET | anakinra | VIAL; SUBCUTANEOUS | 103950 | 002 | 2001-11-14 | Start Trial | Roche Diagnostics Operations, Inc. (Indianapolis, IN) | 2034-03-26 | RX | search | |
| Biovitrum Ab | KINERET | anakinra | VIAL; SUBCUTANEOUS | 103950 | 001 | 2001-11-14 | Start Trial | Roche Diagnostics Operations, Inc. (Indianapolis, IN) | 2034-03-26 | RX | search | |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
International Patent Family for US Patent 10,345,315
| Country | Patent Number | Estimated Expiration |
|---|---|---|
| World Intellectual Property Organization (WIPO) | 2015144767 | Start Trial |
| United States of America | 2017010283 | Start Trial |
| United States of America | 2019277861 | Start Trial |
| >Country | >Patent Number | >Estimated Expiration |
