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Last Updated: September 22, 2020

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Patent: 10,307,505

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Summary for Patent: 10,307,505
Title:Wound dressings for the controlled release of therapeutic agents
Abstract: A wound dressing material for controlled activation of a wound healing therapeutic compound in the presence of a protease enzyme in a wound fluid, the material comprising: a medically acceptable polymer; a wound healing therapeutic agent; an inhibitor of the protease enzyme; and a linker group which is cleavable by the protease enzyme wherein the activities of both the wound healing therapeutic agent and the inhibitor increased by contacting the wound dressing material with a would fluid containing the protease enzyme. For example, the enzyme may be a matrix metalloproteinase, the therapeutic agent may be a reactive oxygen scavenger, and the inhibitor may be a tissue inhibitor of metalloproteinase (TIMP).
Inventor(s): Cullen; Breda Mary (Skipton, GB), Gregory; Sara Jayne (West Yorkshire, GB)
Assignee: KCI USA, INC. (San Antonio, TX)
Application Number:15/612,831
Patent Claims:see list of patent claims

Details for Patent 10,307,505

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bayer Hlthcare TRASYLOL aprotinin INJECTABLE;INJECTION 020304 001 1994-02-07   Start Trial KCI USA, INC. (San Antonio, TX) 2023-11-24 DISCN search
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial KCI USA, INC. (San Antonio, TX) 2023-11-24 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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