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Last Updated: September 18, 2020

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Patent: 10,292,984

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Summary for Patent: 10,292,984
Title:Methods for increasing blood plasma 2\'-deoxyuridine (dUrd) and thymidylate synthase inhibition
Abstract: The present invention provides methods for increasing plasma dUrd levels comprising the administration of 6R-MTHF. The methods of increasing plasma dUrd increase dUrd levels compared to equimolar concentrations of LV. The present invention also provides methods for increasing TS inhibition comprising the administration of 6R-MTHF. The present invention also provides methods for increasing TS inhibition comprising the administration of 6R-MTHF.
Inventor(s): Carlsson; Goran U. (Jonsered, SE), Gustavsson; Bengt (Vastra Froelunda, SE), Odin; Elisabeth (Goteborg, SE), Wettergren; Yvonne (Goteborg, SE), Vedin; Anders (Goteborg, SE)
Assignee: Isofol Medical AB (Goteborg, SE)
Application Number:15/893,235
Patent Claims:see list of patent claims

Details for Patent 10,292,984

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26   Start Trial Isofol Medical AB (Goteborg, SE) 2037-02-14 RX Orphan search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26   Start Trial Isofol Medical AB (Goteborg, SE) 2037-02-14 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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