Patent: 10,238,700
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Summary for Patent: 10,238,700
Title: | Oncolytic virus adjunct therapy with agents that increase virus infectivity |
Abstract: | Provided are adjunct therapies for use in combinations and compositions with an oncolytic virus, such as a vaccinia virus. The adjunct therapies include co-administration and co-formulation of a complement inhibitor and/or a lipid emulsion composition with the oncolytic virus. Also provided herein are therapeutic methods using the adjunct therapies for treatment of disease and conditions employing an oncolytic therapeutic virus, such as for the treatment of hyperproliferative diseases or conditions including tumors or cancers. |
Inventor(s): | Szalay; Aladar A. (Highland, CA), Cappello; Joseph (San Diego, CA), Chen; Nanhai G. (San Diego, CA), Minev; Boris (San Diego, CA) |
Assignee: | Genelux Corporation (San Diego, CA) |
Application Number: | 15/109,214 |
Patent Claims: | see list of patent claims |
Details for Patent 10,238,700
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Emergent Product Development Gaithersburg, Inc. | ACAM2000 | smallpox (vaccinia) vaccine, live | For Injection | 125158 | 08/31/2007 | ⤷ Try a Trial | 2034-01-02 |
Alexion Pharmaceuticals, Inc. | SOLIRIS | eculizumab | Injection | 125166 | 03/16/2007 | ⤷ Try a Trial | 2034-01-02 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |