Upgrade for Complete Access See Plans and Pricing

Serving leading biopharmaceutical companies globally:

AstraZeneca
Harvard Business School
Johnson and Johnson
Medtronic
McKesson
Mallinckrodt

Last Updated: December 1, 2021

DrugPatentWatch Database Preview

Patent: 10,202,429

➤ Subscribe for complete access

« Back to Dashboard

Summary for Patent: 10,202,429
Title:Norrin regulation of cellular production of junction proteins and use to treat retinal vasculature edema
Abstract: A method of tightening inter-cellular junctions in retinal or choroidal vessel cells includes exposing the retinal or choroidal vessel cells to norrin. Upon sufficient contact time, for norrin to selectively up-regulate gene expression of VE-cadherin or claudin-5 in the retinal or choroidal vessel cells, the inter-cellular junctions are tightened. The method is also suitable for treating retinal pigment epithelial cells in wet macular degeneration.
Inventor(s): Trese; Michael T. (Novi, MI), Capone, Jr.; Antonio (Novi, MI), Drenser; Kimberly (Novi, MI)
Assignee: RETINAL SOLUTIONS LLC (Ann Arbor, MI)
Application Number:14/733,729
Patent Claims:see list of patent claims

Details for Patent 10,202,429

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. AVASTIN bevacizumab Injection 125085 2004-02-26 ⤷  Try it Free 2039-02-26
Genentech, Inc. LUCENTIS ranibizumab Injection 125156 2006-06-30 ⤷  Try it Free 2039-02-26
Genentech, Inc. LUCENTIS ranibizumab Injection 125156 2012-08-10 ⤷  Try it Free 2039-02-26
Genentech, Inc. LUCENTIS ranibizumab Injection 125156 2016-10-13 ⤷  Try it Free 2039-02-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

Make Better Decisions: Try a trial or see plans & pricing

Serving leading biopharmaceutical companies globally:

Baxter
Mallinckrodt
AstraZeneca
Boehringer Ingelheim
Dow
Moodys

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.