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Last Updated: September 28, 2020

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Patent: 10,201,544

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Summary for Patent: 10,201,544
Title:Method of synthesising ADCs using affinity resins
Abstract: This invention relates to a solid phase method of synthesizing biomolecule-drug conjugates. In particular, this invention relates to a solid phase method of synthesizing antibody-drug conjugates (ADCs). This invention also relates to intermediate methods of producing immobilized, chemically modified biomolecules, e.g. antibodies. The invention also relates to various uses of capture resins and to biomolecule-drug conjugates, intermediate products and compositions prepared by the methods of the invention.
Inventor(s): Evans; David J. (Chester, GB), McKee; Colin M. (Conwy, GB)
Assignee: ADC Biotechnology Ltd. (St. Asaph, GB)
Application Number:14/786,387
Patent Claims:see list of patent claims

Details for Patent 10,201,544

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25   Start Trial ADC Biotechnology Ltd. (St. Asaph, GB) 2033-04-26 RX Orphan search
Genentech Inc HERCEPTIN HYLECTA trastuzumab; hyaluronidase-oysk INJECTABLE;SUBCUTANEOUS 761106 001 2019-02-28   Start Trial ADC Biotechnology Ltd. (St. Asaph, GB) 2033-04-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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