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Last Updated: September 28, 2020

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Patent: 10,196,365

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Summary for Patent: 10,196,365
Title:Quinazoline derivative, preparation method therefor, and pharmaceutical composition and application thereof
Abstract: Disclosed are a quinazoline derivative, a preparation method therefor, and a pharmaceutical composition and an application thereof. The present invention provides a compound represented by general formula I, a stereoisomer thereof and a pharmaceutical acceptable salt or a solvate thereof. The quinazoline derivative of the present invention has a unique chemical structure, is characterized by irreversibly inhibiting EGFR tyrosine kinase, has high biological activity, apparently improves the inhibiting effect on the EGFR tyrosine kinase, has quite strong tumor inhibiting effect on tumor cells and a transplantation tumor pathological model of animal tumors, and has good market developing prospects. ##STR00001##
Inventor(s): Hong; Jian (Suzhou, CN), Xu; Xin (Suzhou, CN), Le; Xiaoyong (Suzhou, CN), Zhang; Zonghua (Suzhou, CN)
Assignee: ARROMAX PHARMATECH CO., LTD. (Suzhou, Jiangsu, CN)
Application Number:15/504,187
Patent Claims:see list of patent claims

Details for Patent 10,196,365

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Start Trial ARROMAX PHARMATECH CO., LTD. (Suzhou, Jiangsu, CN) 2039-02-26 RX search
Chiron PROLEUKIN aldesleukin VIAL 103293 001 1992-05-05   Start Trial ARROMAX PHARMATECH CO., LTD. (Suzhou, Jiangsu, CN) 2039-02-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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