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Generated: August 24, 2019

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Patent: 10,188,730

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Summary for Patent: 10,188,730
Title:Anti-LAG3 antibodies and antigen-binding fragments
Abstract: The present invention includes antibodies and antigen-binding fragments thereof that specifically bind to human or cynomolgous monkey LAGS as well as immunoglobulin chains thereof and polynucleotides encoding the same along with injection devices comprising such antibodies or fragments. Vaccines including such antibodies and fragments as well as compositions comprising the antibodies and fragments (e.g., including anti-PD1 antibodies) are included in the invention. Methods for treating or preventing cancer or infection using such compositions are also provided. In addition, methods for recombinant expression of the antibodies and fragments are part of the present invention.
Inventor(s): Liang; Linda (Mountain View, CA), Fayadat-Dilman; Laurence (Sunnyvale, CA), De Waal Malefyt; Rene (Sunnyvale, CA), Raghunathan; Gopalan (San Diego, CA)
Assignee: Merck Sharp & Dohme Corp. (Rahway, NJ)
Application Number:15/482,355
Patent Claims:see list of patent claims

Details for Patent 10,188,730

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck Sharp Dohme KEYTRUDA pembrolizumab POWDER, FOR INJECTION SOLUTION, LYOPHILIZED POWDER 125514 001 2014-09-04 ➤ Sign Up Merck Sharp & Dohme Corp. (Rahway, NJ) 2034-08-19 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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