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Last Updated: February 18, 2020

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Patent: 10,183,977

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Summary for Patent: 10,183,977
Title:Stabilized STAT3 decoy oligonucleotides and uses therefor
Abstract: The present invention is based, at least in part, on novel, unimolecular STAT3 oligonucleotide decoys exhibiting increased in vivo stability as compared to previously known decoys which are effective in inhibiting STAT3 when administered systemically. The invention is also based on pharmaceutical compositions comprising these unimolecular decoys, and methods for using these decoys in the treatment of cancer.
Inventor(s): Grandis; Jennifer R. (Pittsburgh, PA), Johnson; Daniel E. (Glenshaw, PA), Ly; Danith (Pittsburgh, PA)
Assignee: UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, PA) CARNEGIE MELLON UNIVERSITY (Pittsburgh, PA)
Application Number:15/611,298
Patent Claims:see list of patent claims

Details for Patent 10,183,977

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Imclone ERBITUX cetuximab VIAL; INTRAVENOUS 125084 001 2004-06-18   Start Trial UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, PA) CARNEGIE MELLON UNIVERSITY (Pittsburgh, PA) 2029-12-17 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 10,183,977

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