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Last Updated: September 21, 2020

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Patent: 10,167,516

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Summary for Patent: 10,167,516
Title:Six-gene biomarker of survival and response to platinum based chemotherapy in serious ovarian cancer patients
Abstract: Described herein are methods of predicting the risk of developing ovarian cancer recurrence of a subject comprising the steps of detecting the expression levels of at least four of the six genes selected from the group consisting of AKT2, KRAS, RAC1, CALM3, RPS6KA2 and YWHAB or the gene products thereof, wherein the presence of increased expression levels of the genes or the gene products is predictive of the increased risk of developing ovarian cancer recurrence in the subject. Kits for practicing the methods are also disclosed.
Inventor(s): Newton; Christina Kendziorski (Madison, WI), Eng; Kevin Hasegawa (Williamsville, NY), Rader; Janet S. (Whitefish Bay, WI), Bradley; William H. (Wauwatosa, WI)
Assignee: Wisconsin Alumni Research Foundation (Madison, WI)
Application Number:15/339,109
Patent Claims:see list of patent claims

Details for Patent 10,167,516

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26   Start Trial Wisconsin Alumni Research Foundation (Madison, WI) 2033-04-19 RX Orphan search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26   Start Trial Wisconsin Alumni Research Foundation (Madison, WI) 2033-04-19 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Dow

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