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Last Updated: September 30, 2020

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Patent: 10,155,808

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Summary for Patent: 10,155,808
Title:Monoclonal antibody against human PrPc and use thereof
Abstract: A monoclonal antibody against human PrPc protein capable of reducing the expression level of transcription factor Twist1 in a targeting mode and inducing macrophage and NK cells to target to rectal cancer tumor cells. The combined drug therapy with the antibody and cetuximab also exhibits inhibitory effect on tumor better than administration of the antibody or cetuximab alone.
Inventor(s): Chen; Quan (Beijing, CN), Li; Baowei (Beijing, CN), Hang; Haiying (Beijing, CN), Du; Lei (Beijing, CN), Wang; Jun (Beijing, CN), Wang; Xiaohui (Beijing, CN)
Assignee: Institute of Zoology, Chinese Academy of Sciences (Beijing, CN)
Application Number:15/351,418
Patent Claims:see list of patent claims

Details for Patent 10,155,808

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Imclone ERBITUX cetuximab VIAL; INTRAVENOUS 125084 001 2004-06-18   Start Trial Institute of Zoology, Chinese Academy of Sciences (Beijing, CN) 2034-05-15 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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