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Last Updated: October 1, 2020

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Patent: 10,155,803

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Summary for Patent: 10,155,803
Title:Multivalent heteromultimer scaffold design and constructs
Abstract: Provided herein are multifunctional heteromer proteins. In specific embodiments is a heteromultimer that comprises: at least two monomeric proteins, wherein each monomeric protein comprises at least one cargo polypeptide, attached to a transporter polypeptide, such that said monomeric proteins associate to form the heteromultimer. These therapeutically novel molecules comprise monomers that function as scaffolds for the conjugation or fusion of therapeutic molecular entities resulting in the creation of bispecific or multivalent molecular species.
Inventor(s): Dixit; Surjit Bhimarao (Richmond, CA), D\'Angelo; Igor Edmondo Paolo (Port Moody, CA), Poon; David Kai Yuen (Richmond, CA)
Assignee: ZYMEWORKS INC. (Vancouver BC, CA)
Application Number:15/355,007
Patent Claims:see list of patent claims

Details for Patent 10,155,803

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bpl ALBUMINEX albumin human SOLUTION 125644 1 2020-05-27   Start Trial ZYMEWORKS INC. (Vancouver BC, CA) 2031-03-03 search
Kedrion S.p.a KEDBUMIN albumin (human) INJECTION, SOLUTION 125384 1 2011-09-15   Start Trial ZYMEWORKS INC. (Vancouver BC, CA) 2031-03-03 search
Octapharma Usa Inc ALBUMIN (HUMAN) albumin human SOLUTION 125154 1 2006-10-17   Start Trial ZYMEWORKS INC. (Vancouver BC, CA) 2031-03-03 search
Csl Behring Llc ALBUMINAR-25 albumin (human) SOLUTION 103955 1 2009-01-06   Start Trial ZYMEWORKS INC. (Vancouver BC, CA) 2031-03-03 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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