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Generated: August 24, 2019

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Patent: 10,143,677

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Summary for Patent: 10,143,677
Title:Taxane analogs for the treatment of brain cancer
Abstract: Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubles at G2-M interface during mitosis but is not a substrate for MDR protein. In particular, the present application relates to the use of an orally effective abeo-taxane, alone or in combination with temozolomide or bevacizumab, for the treatment of brain cancer.
Inventor(s): McChesney; James D. (Etta, MS), Tapolsky; Gilles H. (Louisville, KY), Emerson; David L. (Longmont, CO), Marshall; John (Washington, DC), Kurman; Michael (Upper Saddle River, NJ), Modiano; Manuel (Tuscon, AZ)
Assignee: TAPESTRY PHARMACEUTICALS, INC. (Atlanta, GA)
Application Number:15/483,551
Patent Claims:see list of patent claims

Details for Patent 10,143,677

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26 ➤ Sign Up TAPESTRY PHARMACEUTICALS, INC. (Atlanta, GA) 2027-02-28 RX search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26 ➤ Sign Up TAPESTRY PHARMACEUTICALS, INC. (Atlanta, GA) 2027-02-28 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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