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Last Updated: January 20, 2020

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Patent: 10,131,932

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Summary for Patent: 10,131,932
Title:Method for assaying a protease
Abstract: A method of determining generation of an activated protease in a biological sample is provided. The method comprises the steps of exposing a biological sample to a substrate for the activated protease, wherein the substrate comprises a detectable label linked to a cleavage sequence for the activated protease by C-terminal and N-terminal spacers that form a beta-sheet, and wherein the detectable label emits a first signal associated with the substrate and second signal associated with a cleaved product; and determining the generation of the activated protease by measuring the change in the first or second signal over time.
Inventor(s): Qiao; Shengjun (Hamilton, CA), Gross; Peter (Ancaster, CA)
Assignee: McMaster University (Hamilton, Ontario, unknown)
Application Number:15/066,509
Patent Claims:see list of patent claims

Details for Patent 10,131,932

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial McMaster University (Hamilton, Ontario, unknown) 2039-02-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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