Method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
Methods are provided for drying a particle. Specifically, there is provided a spray-dried diketopiperazine-insulin particle formulation having improved aerodynamic performance and in which the active agent is more stabile and efficiently delivered as compared to that of the lyophilized diketopiperazine-insulin formulation. The dry powders have utility as pharmaceutical formulations for pulmonary delivery.
Wilson; Bryan R. (Brewster, NY), Grant; Marshall (Newtown, CT)
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