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Last Updated: September 21, 2020

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Patent: 10,100,115

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Summary for Patent: 10,100,115
Title:Methods for the treatment of vascularizing cancers
Abstract: The invention concerns therapeutic compositions for the treatment of vascularizing cancers, especially, glioblastoma. In particular, the invention is directed to compositions that comprise a molecule having a binding ability that is specific for B7-H3 and a molecule having a binding ability that is specific for a cell-surface factor (or its receptor) that is involved in promoting tumor angiogenesis (especially VEGF or its receptor, VEGFR). The invention is additionally directed to the use of such compositions in the treatment of such cancers, and in particular, in the treatment of glioblastoma.
Inventor(s): Chi; Andrew S. (Boston, MA)
Assignee: MacroGenics, Inc. (Rockville, MD)
Application Number:15/118,010
Patent Claims:see list of patent claims

Details for Patent 10,100,115

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26   Start Trial MacroGenics, Inc. (Rockville, MD) 2034-02-12 RX Orphan search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26   Start Trial MacroGenics, Inc. (Rockville, MD) 2034-02-12 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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