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Last Updated: September 26, 2022

Patent: 10,093,732


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Summary for Patent: 10,093,732
Title:Antagonists of IL-6 to prevent or treat thrombosis
Abstract: The present invention is directed to therapeutic methods using IL-6 antagonists such as antibodies and fragments thereof having binding specificity for IL-6 to prevent or treat thrombosis in diseases associated with abnormal blood coagulation or fibrinolysis. In preferred embodiments these patients will comprise those exhibiting elevated D-dimer or other coagulation cascade related proteins and optionally will further exhibit elevated C reactive protein prior to treatment. The subject therapies also may include the administration of other actives such as chemotherapeutics, anti-coagulants, statins, et al.
Inventor(s): Smith; Jeffrey T. L. (Bellevue, WA)
Assignee: ALDERBIO HOLDINGS LLC (Las Vegas, NV)
Application Number:14/933,141
Patent Claims:see list of patent claims

Details for Patent 10,093,732

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Bausch Health Us, Llc IPRIVASK desirudin For Injection 021271 04/04/2003 See Plans and Pricing 2028-11-25
Janssen Biotech, Inc. REOPRO abciximab Injection 103575 12/22/1994 See Plans and Pricing 2028-11-25
Genentech, Inc. RITUXAN rituximab Injection 103705 11/26/1997 See Plans and Pricing 2028-11-25
Eli Lilly And Company ERBITUX cetuximab Injection 125084 02/12/2004 See Plans and Pricing 2028-11-25
Eli Lilly And Company ERBITUX cetuximab Injection 125084 03/28/2007 See Plans and Pricing 2028-11-25
Novartis Pharmaceuticals Corporation ARZERRA ofatumumab Injection 125326 10/26/2009 See Plans and Pricing 2028-11-25
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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Serving leading biopharmaceutical companies globally:

Merck
Colorcon
Harvard Business School
Express Scripts
Baxter
Mallinckrodt

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